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Parenteral nutrition should only be infused via a central vein.

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Parenteral nutrition can be infused via a central vein or a peripheral vein. However, it is generally preferred to infuse it through a central vein as it allows for a higher concentration of nutrients and reduces the risk of complications such as phlebitis or thrombosis. Infusing parenteral nutrition through a peripheral vein is usually considered when central access is not available or contraindicated.

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